It is clearly a USB communication problem.
Maybe try to connect the QUADRO directly to a USB port of the mainboard. You could also disconnect the hub to perform that test. If you have another PC around, you could test it there too. Connecting power and USB is enoough.
You can also try the follwing. Disconnect all of our devices from USB but the QUADRO.
Download the tool USBDeview (Freeware) from
https://www.nirsoft.net/utils/usb_devices_view.html
Start the program with admin rights. It will show all USB devices that are currently attached and have been attached in the past. There is a column called VendorID. Click on its name to sort the list and look for devices with the ID "0c70". Please mark all "0c70" entries and then right click and select uninstall selected devices.
Shut down the PC afterwards and also disconnect it completely from power for a few seconds. Power it back on and check if QUADRO is detected in the aquasuite now. If so, shut down the system again and connect the other devices.
If QUADRO is not detected by aquasuite, but you can see "0c70" entries in the tool again after the restart, please mark them and export an HTML report (right click) for these items so that we can have a look what is going on there.