All changes are saved immediately in the Quadro or Octo.
However, if you are working with profiles, you must also save these changes in the corresponding profile before you switch to another profile, otherwise the changes will be lost.
Linux or BIOS
The Aquasuite does not run under Linux or when you are in the BIOS.
The Octo can therefore only regulate the fans according to e.g. temperatures that are available to the Octo without the Aquasuite (e.g. a hard-wired temperature sensor to the Octo).
Are you using a control parameter (under Windows) e.g. from HWInfo or a virtual sensor from the Playground to control the Fans?
This parameter is not available under Linux (and in the BIOS) and the Octo uses the set fallback value that can be defined for each output.
In your case this fallback value is probably set to 100%?